Site performance is transformed by scientific leadership.

Scientific leadership in clinical trials facilitates study operations through peer-to-peer engagement with investigators.

The George Clinical Scientific Leadership model offers:

• A scientifically sound, pragmatic approach that informs strong operational delivery
• Protocol alignment with clinical practice across geographies
• Motivated and engaged investigators
• Robust communication conduits between the investigators, study teams, steering committees and the sponsor

Professor Stephen MacMahon, Principal Director, The George Institute for Global Health

Delivery of our scientific leadership model leverages the reputation and extensive global clinical investigator networks of one of our partners in research, The George Institute of Global Health.

Site performance is transformed by scientific leadership.

In the traditional study operations model, site engagement is typically performed by clinical research associates (CRAs). With George Clinical’s scientific leadership model, we provide a framework that enables active peer-to-peer communication and action pathways between global scientific committee members, national scientific leaders and principal investigators.

Examples of activities within our scientific leadership service model include:

• Trial design and strategy
• Protocol development
• Publication oversight and writing
• National leader selection and appointment
• Content development for investigator meetings
• Liaison with the various trial committees, national leaders and operations teams
• Support site identification and recruitment activities
• Support patient recruitment and retention activities
• Advise operational teams on dealing with challenges arising in the clinical trial environment
• Scientific committee management, such as selection, appointment, contracting and charter preparations
• Administrative and communication support between various study committees

By engaging its scientific leadership, George Clinical is able to recruit international experts to Steering, Adjudication and Data Safety Committees.

George Clinical supports sponsors in the setup of key trial committees by selecting, and contracting experienced committee members whom we access through our global scientific networks.

George Clinical’s scientific teams are experts in the establishment and operational management of committees, including charter development, meeting organisation and chairing roles.

Investigator Initiated Trials (IIT) are an essential part of clinical research offering unique insight from a real-world clinical perspective. George Clinical’s scientific leaders are well placed to identify and address requirements for innovative and pragmatic clinical trials.

George Clinical’s Investigator Initiated Trials are fully supported by the qualified staff of George Clinical, who manage all aspects of the project from study design through data-lock, analysis, and manuscript. Our team possesses a deep understanding of the clinical landscape and emerging trends in clinical practice.